Publications

Mi trabajo científico ha sido publicado en revistas prestigiosas como Journal of the American College of Cardiology, Circulation y Scientific Reports, contribuyendo a la comprensión de las influencias genéticas en la salud cardiovascular. Además, tengo amplia experiencia revisando y editando manuscritos científicos en diversas áreas terapéuticas, garantizando una comunicación científica de alta calidad.

Articles

Effectiveness, safety and discontinuation rates of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) in people with HIV using real-world data:a systematic review and meta-analysis

Chivite, I.; Berrocal, L.; de Lazzari, E.; Navadeh, S.; Lluís-Ganella, C.; Inciarte, A.; de la Mora, L.; González-Cordón, A.; Martínez-Rebollar, M.; Laguno, M.; Torres, B; Blanco, JL.; Martinez, E.; Mallolas, J.; Ambrosioni, J.
J Antimicrob Chemother. Aug 1;79(8):1775-1783. PMID

Real-world discontinuations due to neuropsychiatric symptoms in people living with HIV treated with second-generation integrase inhibitors: a systematic review

Pérez-Valero, I.: Corona, D.: Martinez, N.; Lopez-Cavanillas, M.; Lluís-Ganella, C.; Luque, I.
Expert Rev Anti Infect Ther. Jun;21(6):655-665. PMID

Weighted Multi-marker Genetic Risk Scores for Incident Coronary Heart Disease among Individuals of African, Latino and East-Asian Ancestry

Iribaren, C.; Lu, M.; Jorgenson, E.; Martínez, M; Lluis-Ganella, C.; Subirana, I.; Salas, E.; Elosua, R.
Sci Rep. 8(1):6853. PMID

Prevalence of genetically confirmed familial hypercholesterolemia in patients with acute coronary syndromes

Amor-Salamanca, A.; Castillo, S.; Gonzalez-Vioque, E.; Dominguez, F.; Quintana, L.; Lluís-Ganella, C.; Escudier, J.M.; Ortega, J.; Lara-Pezzi, E.; Alonso-Pulpon, L.; Garcia-Pavia, P.
J Am Coll Cardiol. 70(14):1732-174

DNA methylation and obesity traits: An epigenome-wide association study. The REGICOR study

Sayols-Baixeras, S.; Subirana, I.; Fernández-Sanlés, A.; Sentí, M.; Lluís-Ganella, C.; Marrugat, J.; Elosua, R.
Epigenetics. 12(10):909-916. PMID

Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach

Sayols-Baixeras, S.; Subirana, I.; Lluís-Ganella, C.; Civeira, F.; Roquer, J.; Do, A.N.; Absher, D.; Cenarro, A.; Muñoz, D.; Soriano-Tárraga, C.; Jiménez-Conde, J.; Ordovas, J.M.; Senti, M.; Aslibekyan, S.; Marrugat, J.; Arnett, D.K.; Elosua, R.
Hum Mol Genet. 28(8):1402. PMID

DNA Methylation and High-Density Lipoprotein Functionality-Brief Report: The REGICOR Study

Sayols-Baixeras, S.; Hernaez, A.; Subirana, I.; Lluís-Ganella, C.; Muñoz, D.; Fitó, M.; Marrugat, J.; Elosua, R.
Arterioscler Thromb Vasc Biol. 37(3):567-569. PMID

Clinical Utility of Multi-marker Genetic Risk Scores for Prediction of Incident Coronary Heart Disease. A Cohort Study among over 51 Thousand Individuals of European Ancestry

Iribarren, C.; Lu, M.; Jorgenson, E.; Martinez, M.; Lluís-Ganella, C.; Subirana, I.; Salas, E.; Elosua, R.
Circ Cardiovasc Genet. 9(6):531-540. PMID

Identification of a new locus and validation of previously reported loci showing differential methylation associated with smoking. The REGICOR study

Sayols-Baixeras, S.; Lluís-Ganella, C.; Subirana, I.; Salas, L.A.; Vilahur, N.; Corella, D.; Muñoz, D.; Segura, A.; Jimenez-Conde, J.; Moran, S.; Soriano-Tárraga, C.; Roquer, J.; Lopez-Farré, A.; Marrugat, J.; Fitó M.; Elosua, R.
Epigenetics. 11(2):174. PMID

Cardiovascular Risk Factors and Ischemic Heart Disease: Is the Confluence of Risk Factors Greater Than the Parts? A Genetic Approach

Elosua, R.; Lluís-Ganella, C.; Subirana, I.; Havulinna, A.; Läll, K.; Lucas, G.; Sayols-Baixeras, S.; Pietilä, A.; Alver, M.; Cabrera,A.; Sentí, M.; Siscovick, D.; Mellander, O.; Fischer, K.; Salomaa, V.; Marrugat, M.
Circ Cardiovasc Genet. 9(3):279-86. PMID

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome

Sinisalo, J.; Vlachopoulou, E.; Marchesani, M.; Nokelainen, J.; Mäyränpää, MI.; Lappalainen, J.; Paakkanen, R.; Wennerström, A.; Salli, K.; Niemi, HJ.; Männistö, S.; Salo, P.; Junttila, J.; Eskola, M.; Nikus, K.; Arstila, TP.; Perola, M.; Huikuri, H.; Karhunen, PJ.; Kovanen, PT.; Palotie, A.; Havulinna, AS.; Lluís-Ganella, C.; Marrugat, J.; Elosua, R.; Salomaa, V.; Nieminen, MS.; Lokki, ML.
Circ Cardiovasc Genet. 9(1):55-63. PMID

Analysis of gene-gene interactions among common variants in candidate cardiovascular genes in coronary artery disease

Musameh, M.; Wang, W.; Nelson, C.; Lluís-Ganella, C.; Subirana, I.; Elosua, R.; Hall, A.; Kathiresan, S.; Samani, N.; Tomaszewski, M.
PLoS One. 10(2):e0117684. PMID

Association between rs2200733 and rs7193343 genetic variants and atrial fibrillation in a Spanish population, and meta-analysis of previous studies

Ferran, A.; Alegret, JM.; Subirana, I.; Aragonès, G.; Lluís-Ganella, C.; Romero-Menor, C.; Planas, F.; Joven, J.; Elosua, R.
Rev Esp Cardiol (Engl Ed). 67(10):822-9. PMID

Update in Cardiology: Vascular Risk and Cardiac Rehabilitation

Galve, E.; Alegria, E.; Cordero, A.; Facila, L.; Fernandez de Bobadilla, J.; Lluís-Ganella, C.; Mazon, P.; Zarzosa, CP.; Gonzalez-Juanatey, JR.
Rev Esp Cardiol (Engl Ed). 67(3):203-10. PMID

Hypothesis-based Analysis of Gene-Gene Interactions and Risk of Myocardial Infarction

Lucas, G.; Lluís-Ganella, C.; Subirana, I.; Musameh, MD.; Gonzalez, JR.; Nelson, CP.; Sentí, M.; The Myocardial Infarction Genetics Consortium; The Wellcome Trust Case Control Consortium; Schwartz, SM.; Siscovick, D.; O'Donnell, CJ.; Melander, O.; Salomaa, V.; Purcell, S.; Altshuler, D.; Samani, NJ.; Kathiresan, S.; Elosua, R.
PLoS One. 7(8):e41730. PMID

Assessment of the value of a genetic risk score in improving the estimation of coronary risk

Lluís-Ganella, C.; Subirana, I.; Lucas, G.; Tomás, M.; Muñoz, D.; Sentí, M.; Salas, E.; Sala, J.; Ramos, R.; Ordovas, JM.; Marrugat, J.; Elosua, R.
Atherosclerosis. 222(2):456-63. PMID

Post-Genomic Update on a Classical Candidate Gene for Coronary Artery Disease: ESR1

Lucas, G.; Lluís-Ganella, C.; Subirana, I.; Sentí, M.; Willenborg, C.; Musameh, MD.; Schwartz, SM.; O'Donnell, CJ.; Melander, O.; Salomaa, V.; Elosua, R.
Circ Cardiovasc Genet. 4(6):647-54. PMID

Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel

Zabalza, M.; Subirana, I.; Sala, J.; Lluís-Ganella, C.; Lucas, G.; Tomás, M.; Masiá, R.; Marrugat, J.; Brugada, R.; Elosua, R.
Heart. 98(2):100-8. PMID

Additive Effect of Multiple Genetic Variants on the Risk of Coronary Artery Disease

Lluís-Ganella, C.; Lucas, G.; Subirana, I.; Senti, M.; Jimenez-Conde, J.; Marrugat, J.; Tomas, M.; Elosua, R.
Rev Esp Cardiol. 63(8):925-33. PMID

Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women

Lluís-Ganella, C.; Lucas, G.; Subirana, I.; Escurriol, V.; Tomas, M.; Senti, M.; Sala, J.; Marrugat, J.; Elosua, R.
Atherosclerosis. 207(2):480-6. PMID

Exact distribution of genetic risk score at the population level

Subirana, I.; Lucas, G.; Esnaola, M.; Lluís-Ganella, C.; Elosua, R.; Gonzalez, JR.
CEB-EIB

Genetic profile of the SCN5A gene in Brugada Syndrome

Coll, M.; Allegue, C.; Pérez-Serra, A.; Picó, F.; Mademont-Soler, I.; Lluís-Ganella, C.; Elosua, R.; Campuzano, O.; Oliva, A.; Partemi, S.; Iglesias, A.; Brugada, R.
Submitted

Evaluation of the role of a genetic risk score for blood pressure on risk of ischemic stroke subtypes

Lucas, G.; Subirana, I.; Lluís-Ganella, C.; Domingues-Montanari, S.; Roquer, J.; Rabionet, R.; Obach, V.; Krupinski, J.; Iniesta, JA.; Martí-Fàbregas, J.; Goyenechea, E.; Jimenez, J.; Elosua, E.
Submitted

Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia

Simino, J.; Shi, G.; Bis, JC.; Chasman, DI.; Ehret, GB.; Gu, X.; Guo, X.; Hwang, SJ.; Sijbrands, E.; Smith, AV.; Verwoert, GC.; Bragg-Gresham, JL.; Cadby, G.; Chen, P.; Cheng, CY.; Corre, T.; de, Boer, RA.; Goel, A.; Johnson, T.; Khor, CC.; LifeLines Cohort Study; Lluís-Ganella, C.; Luan, J.; Lyytikäinen, LP.; Nolte, IM.; Sim, X.; Sõber, S.; van, der, Most, PJ.; Verweij, N.; Zhao, JH.; Amin, N.; Boerwinkle, E.; Bouchard, C.; Dehghan, A.; Eiriksdottir, G.; Elosua, R.; Franco, OH.; Gieger, C.; Harris, TB.; Hercberg, S.; Hofman, A.; James, AL.; Johnson, AD.; Kähönen, M.; Khaw, KT.; Kutalik, Z.; Larson, MG.; Launer, LJ.; Li, G.; Liu, J.; Liu, K.; Morrison, AC.; Navis, G.; Ong, RT.; Papanicolau, GJ.; Penninx, BW.; Psaty, BM.; Raffel, LJ.; Raitakari, OT.; Rice, K.; Rivadeneira, F.; Rose, LM.; Sanna, S.; Scott, RA.; Siscovick, DS.; Stolk, RP.; Uitterlinden, AG.; Vaidya, D.; van, der, Klauw, MM.; Vasan, RS.; Vithana, EN.; Völker, U.; Völzke, H.; Watkins, H.; Young, TL.; Aung, T.; Bochud, M.; Farrall, M.; Hartman, CA.; Laan, M.; Lakatta, EG.; Lehtimäki, T.; Loos, RJ.; Lucas, G.; Meneton, P.; Palmer, LJ.; Rettig, R.; Snieder, H.; Tai, ES.; Teo, YY.; van, der, Harst, P.; Wareham, NJ.; Wijmenga, C.; Wong, TY.; Fornage, M.; Gudnason, V.; Levy, D.; Palmas, W.; Ridker, PM.; Rotter, JI.; van, Duijn, CM.; Witteman, JC.; Chakravarti, A.; Rao, DC.
Am J Hum Genet. 95(1):24-38. PMID

Book Chapters & Reviews

What is a genetic test and which tipe of information can it provide?

Lluís-Ganella, C.; Marrugat, J.; Elosua, R.
In press

Update in Cardiology: Vascular Risk and Cardiac Rehabilitation

Galve, E.; Alegria, E.; Cordero, A.; Facila, L.; Fernandez de Bobadilla, J.; Lluís-Ganella, C.; Mazon, P.; Zarzosa, CP.; Gonzalez-Juanatey, JR.
Rev Esp Cardiol. pii: S0300-8932(13)00525-3PMID

Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants

Sayols-Baixeras, S.; Lluís-Ganella, C.; Lucas, G; Elosua, R.
The Application of Clinical Genetics. 7:15-32PMID

Papel de los factores genéticos y otros biomarcadores en la estimación del riesgo y la prevención cardiovascular

Elosua, R.; Lluís-Ganella, C.; Fitó, M.
Retos actuales en el diagnóstico y manejo del SCA en España, Sociedad Española de CardiologíaPMID

Research Into the Genetic Component of Heart Disease: From Linkage Studies to Genome-Wide Genotyping

Elosua, R.; Lluís-Ganella, C.; Lucas, G.
Rev Esp Cardiol Supl. 9(supl.B)PMID